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Free · 2026 · 10% of the NHA CCMA CCMA Foundational Knowledge and Basic Science practice questions

Foundational Knowledge and Basic Science is 10% of the NHA CCMA. Answer 10 questions (6 on Foundational Knowledge and Basic Science) and see your score by domain, with every answer explained. Free, no sign-up.

Question 1 of 10Foundational Knowledge and Basic Science diagnostic
Foundational Knowledge and Basic Science · 10% of the NHA CCMA

A physician tells a patient that, because of a recent seizure, he may not drive until he is cleared. The patient nods quietly to the physician. At checkout, he angrily yells at the front-desk staff about a $20 copay. Which defense mechanism is the patient most likely using?

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Scope of practice, medical terminology, basic pharmacology, nutrition and psychology.

What the NHA CCMA exam tests in Foundational Knowledge and Basic Science

  • Health care systems and settings: MA scope of practice and titles; roles and credentials of providers and allied health staff; licensure vs certification; care delivery models (PCMH, ACO, hospice, home health, mobile units); telehealth and patient portals; payment models; general vs specialty care; ancillary and complementary services
  • Medical terminology: abbreviations, acronyms and symbols; The Joint Commission 'Do Not Use' list; word building (roots, prefixes, suffixes, plurals); lay vs medical terms; positional and directional terms
  • Basic pharmacology: drug classes, indications and common drugs; controlled substance schedules; side vs adverse effects and indications vs contraindications; metric/household measurement and dosage calculations; dosage forms; look-alike/sound-alike drugs; routes; pharmacokinetics (ADME); rights of medication administration; storage and disposal; drug references and FDA rules
  • Nutrition: nutrients, dietary guidelines and food labels; diets for diseases (diabetes, kidney disease, celiac); vitamins and supplements; eating disorders
  • Psychology: developmental stages; signs of common mental health conditions (anxiety, depression, PTSD, ADHD); environmental and socioeconomic stressors; psychology of disability and illness; defense mechanisms; end of life and stages of grief

High-yield foundational knowledge and basic science facts

  • Certification is voluntary and comes from a private body: CCMA (NHA), CMA (AAMA), RMA (AMT), NCMA (NCCT). Licensure is mandatory and state-granted (MD, DO, PA, NP, RN, LPN). Registration means being listed on an official registry.
  • MAs work under provider supervision. They do not diagnose, prescribe, interpret results for patients or give independent medical advice.
  • Care models: PCMH = a primary-care team coordinates all of a patient's care. ACO = providers share accountability for the cost and quality of a population. Hospice = comfort care for a prognosis of about 6 months or less, with curative treatment stopped. Palliative = symptom relief at any stage, and treatment may continue. Home health = skilled care in the home. Mobile units = screenings and vaccines brought to the community.
  • Telehealth types: synchronous (live video or phone), asynchronous or store-and-forward (images, portal messages) and remote patient monitoring (home BP cuff, glucometer). Patient portals offer secure messages, results, refill requests and scheduling.
  • Payment models: fee-for-service pays per service. Capitation pays a fixed amount per member per month regardless of visits. Value-based or pay-for-performance pays for quality outcomes. Bundled payment is one payment per episode of care.
  • General (primary) care vs specialty care (cardiology, dermatology and others, often needing a referral). Ancillary services: lab, imaging, PT/OT, pharmacy. Complementary services: acupuncture, chiropractic, massage.
High-yield word parts
PartMeaningExample
-ectomysurgical removalappendectomy
-otomycutting into (incision)tracheotomy
-ostomycreating a new openingcolostomy
-plastysurgical repairrhinoplasty
-scopyvisual examcolonoscopy
-centesispuncture to remove fluidamniocentesis
-itis / -algiainflammation / painarthritis / myalgia
-emia / -peniablood condition / deficiencyanemia / leukopenia

The full CCMA High-Yield Cram Sheet comes with full prep.

Common foundational knowledge and basic science traps

  • -ostomy (new opening) vs -otomy (incision) vs -ectomy (removal).
  • Proximal/distal describe limbs relative to the trunk; medial/lateral describe position relative to the midline.
  • Side effect (expected, mild) vs adverse effect (harmful); indication vs contraindication.
  • Convert units (g to mg, lb to kg) before using the dosage formula.
  • C-II has no refills; C-III and C-IV allow up to 5 refills within 6 months.
  • Never crush ER, XR, SR or enteric-coated tablets.
  • Varicella-containing vaccines go in the freezer, not the refrigerator.
  • Hospice requires a limited prognosis and stops curative care; palliative care can happen alongside treatment.

Free CCMA foundational knowledge and basic science practice questions

Question 1

While rooming a patient, the medical assistant is asked by the patient, "My hemoglobin A1c came back at 7.2%. Does that mean I have diabetes?" Which response is within the medical assistant's scope of practice?

  1. A"Yes, anything above 6.5% is in the diabetic range, so you do have diabetes."
  2. B"The provider will review your results with you and explain what they mean during today's visit."
  3. C"No, that is only slightly high, so there is nothing to worry about."
  4. D"Let me pull up the reference range and walk you through what your number means."
Show answer and explanation

Answer: B. Interpreting test results and making a diagnosis belong to the licensed provider. The MA appropriately refers the question to the provider.

Why not A: Telling the patient they have diabetes is a diagnosis, which is outside the MA's scope.

Why not C: This interprets the result and gives false reassurance, both of which are outside the MA's scope.

Why not D: Explaining what a result means is still interpretation. That responsibility belongs to the provider, not the MA.

Remember: Medical assistants do not diagnose or interpret test results; they refer those questions to the provider.

Question 2

A medical assistant is entering a provider's verbal medication order into the EHR. Which entry complies with The Joint Commission's official 'Do Not Use' list?

  1. ALisinopril 10 mg daily
  2. BLisinopril 10 mg qd
  3. CLisinopril 10 mg Q.O.D.
  4. DLisinopril 10.0 mg daily
Show answer and explanation

Answer: A. The frequency is spelled out as "daily" and the dose has no trailing zero, so the entry uses no prohibited abbreviation or notation.

Why not B: QD, in any form, is on the Do Not Use list because it can be misread as QID (four times daily). The word "daily" should be written out.

Why not C: QOD is on the Do Not Use list because it can be misread as QD or QID. "Every other day" should be written out.

Why not D: A trailing zero is prohibited because a missed decimal point turns 10.0 mg into 100 mg, a tenfold overdose.

Remember: The Joint Commission prohibits U, IU, QD, QOD, trailing zeros, missing leading zeros, and MS/MSO4/MgSO4, so write "daily" and "every other day" in full.

Question 3

A family practice signs a contract with an insurer. Under the contract, the insurer pays the practice $45 per member per month for every enrolled patient, whether that patient has zero visits or ten visits that month. Which payment model is this?

  1. ACapitation
  2. BFee-for-service
  3. CBundled payment
  4. DPay-for-performance
Show answer and explanation

Answer: A. Capitation pays a fixed amount per enrolled patient for a set period, regardless of how many services the patient actually uses.

Why not B: In fee-for-service, the provider is paid separately for each visit or service performed. Payment would therefore rise with the number of visits.

Why not C: A bundled payment is one combined payment for all services in a defined episode of care, such as a knee replacement. It is not a monthly fee per enrolled member.

Why not D: Pay-for-performance gives providers bonuses or penalties based on meeting quality measures. It does not by definition pay a flat monthly amount per patient.

Remember: Capitation means a fixed per-member-per-month payment, no matter how many services the patient uses.

Question 4

Before an abdominal examination, the provider tells the medical assistant to place the patient in the supine position. Which instruction should the MA give the patient?

  1. A"Please sit up on the table with the head of it raised to about 45 degrees."
  2. B"Please lie flat on your back, face up, with your legs straight out."
  3. C"Please lie flat on your stomach, face down, with your head to one side."
  4. D"Please lie on your back, face up, with your knees bent and feet flat."
Show answer and explanation

Answer: B. Supine means lying flat on the back, face up, with the legs extended.

Why not A: This describes a semi-sitting position (Fowler's/semi-Fowler's, with the head raised about 45 degrees), not a flat supine position.

Why not C: This describes the prone position, which is the opposite of supine.

Why not D: This is the dorsal recumbent position. It is face up, but the bent knees make it different from supine.

Remember: Supine is flat on the back, face up, legs extended; prone is face down; dorsal recumbent is face up with knees bent.

Question 5

A patient taking warfarin asks whether he needs to change his diet. The provider wants him to keep a steady intake of leafy green vegetables such as spinach and kale rather than suddenly increasing or cutting them. Which vitamin in these foods affects warfarin's action?

  1. AVitamin D
  2. BVitamin B12
  3. CVitamin C
  4. DVitamin K
Show answer and explanation

Answer: D. Vitamin K is needed to make clotting factors and works against warfarin, so sudden changes in intake alter the INR.

Why not A: Vitamin D promotes calcium absorption and bone health and does not cause significant warfarin interactions.

Why not B: Vitamin B12 is needed for red blood cell formation and nerve function, not clotting factor production.

Why not C: Vitamin C supports immune function and wound healing but does not directly counteract warfarin.

Remember: Patients on warfarin should keep vitamin K intake (leafy greens) consistent rather than avoid it, because changes in intake affect clotting.

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